Table of Contents
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Foreword, by Michael Harris, Director of Medicines: The Inside Story
Preface and Acknowledgments, by the editors, Elaine C. Stroud, and Gregory J. Higby
Medicines in American Society -- A Personal View, by C. Everett Koop
Chapter 1: The History of Therapeutics
Old Drugs, Old and New History, by John M. RiddleThe Therapeutic Crisis of the Eighteenth Century, by J. Worth Estes
The Road to 20th-Century Therapeutics: Shifting Perspectives and Approaches, by Guenther B. Risse
Chapter 2: Case Studies of Drug Discovery
From Alkaloids to Arsenicals: Systematic Drug Discovery Before the First World War, by John ParascandolaThe Inside Story of the Discovery of Insulin, by Michael Bliss
M&B 693 (Sulfapyridine), by John E. Lesch
The Introduction of the Thiazides: A Case Study in 20th-Century Therapeutics, by Robert M. Kaiser
Planning and Serendipity: The Search for a Nonaddicting Opiate Analgesics and the Nature of Drug Development, by Caroline Jean Acker
Chapter 3: The Disciplines of Medicine Making: Current and Future Trends
Current and Future Trends in Medicinal Chemistry, by John A. MontgomeryPharmacology: Current and Future Trends, by George A. Condouris
The Recent History of Pharmacognosy, by Varro E. Tyler
Recent Trends and the Future of Pharmaceutics, by George Zografi
Clinical Testing: New Developments and Old Problems, by Mark Parascandola
Chapter 4: Medicines to Market and Patient: Twentieth Century Trends
Recent Trends in Drug Development, by Louis LasagnaRegulation of Prescription Drugs in the United States, by John P. Swann
Marketing Pharmaceuticals, by Mickey Smith
Physician-Patient-Pharmacist Interaction, by Paul L. Ranelli
The Global Impact of Medicines, by William H. Foege
Concluding Remarks, by Gregory J. Higby